Virus autoimmune response




















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April 24, It usually causes no symptoms or only a brief, mild illness. These symptoms can last for two to four weeks. After infection, EBV becomes dormant, and people remain infected throughout their lives without any symptoms.

Previous studies suggested that EBV infection may play a role in the development of systemic lupus erythematosus and other autoimmune illnesses. However, the possible mechanisms to explain this relationship were unknown. A team of researchers led by Dr. The innate immune response forms the first line of defense against invading pathogens. Innate immunity includes barriers and a variety of cells and molecules that are part of the rapid response to threats to our health. In this interactive you will be introduced to the various aspects of the innate immune response and the ways in which they work together to prevent and control infection.

While the immune system protects us from many pathogens, the inflammation that occurs as part of the immune response can also damage our own tissues and impair the function of our organs when pathogens stimulate a very strong response. In this interactive, you will learn how the innate immune response acts against an invading pathogen. Innate immunity can help protect us from a variety of pathogens, including the coronavirus that causes COVID, though the specifics and the efficacy of the response can differ depending on the type of pathogen.

While the innate immune response is able to prevent or control some infections, it is limited in the ways in which it can react. The adaptive immune response, which includes both B cell-based humoral immunity and T cell-based cellular immunity, reacts much more specifically and powerfully to invading pathogens.

B cells produce antibodies that help to control microbial invasion in a variety of ways, as described in this interactive. With your new knowledge about antibodies, you are ready to see an example of the B cell response in action. For general feedback, use the public comments section below please adhere to guidelines. Your feedback is important to us. However, we do not guarantee individual replies due to the high volume of messages. Your email address is used only to let the recipient know who sent the email.

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By using our site, you acknowledge that you have read and understand our Privacy Policy and Terms of Use. Home Immunology. More information: Lili Gu et al, Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7, Nature Communications DOI: Provided by Trinity College Dublin.

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